Voltammetric and ultraviolet–visible spectroscopic studies on the interaction of etoposide with deoxyribonucleic acid

 The interaction of anticancer drug etoposide (ETO) with salmon sperm double 
strand deoxyribonucleic acid (ss dsDNA) in aqueous solution and immobilized on a screen-
printed carbon electrode (SPCE) has been thoroughly explored using voltammetric 
techniques. UV–vis absorption spectroscopic technique was also employed to probe the 
interaction between the ETO and ss dsDNA in solution. ETO showed two oxidation peaks in 
phosphate buffer solutions (20 mM, pH 4.5 and 7.4). The changes in the anodic current ...