Three new cembranoid-type diterpenes from Red Sea soft coral Sarcophyton glaucum: Isolation and antiproliferative activity against HepG2 cells

Abstract Three new cembranoids: sarcophytolol (1), sarcophytolide B (2), and 
sarcophytolide C (3), along with three known metabolites: 10 (14) aromadendrene (4), 
deoxosarcophine (5), and sarcophine (6) were obtained from the soft bodied coral 
Sarcophyton glaucum. The structures were determined based on spectroscopic 
measurements (NMR, UV, IR and MS). Compounds 1, 3, and 4 had similar significant 
cytotoxic effects towards HepG2 (Human hepatocellular liver carcinoma; IC 50= 20 μM). 2 ...